Scleroderma Renal Crisis - Diagnosis and management Diaqnosis • De novo arterial hypertension of normotensive form +++ • Proteinuria > 2+ • Hematuria > 2+ • Thrombocytopenia < 100 G/L • Hemolysis • Increased serum creatinine >50% • Signs of thrombotic microangiopathy Therapeutic manaqement • Angiotensin-converting enzyme inhibitors +++ • If needed to control blood pressure: IV nicardipin/urapidil • Avoid diuretics and ß-blockers • Discuss dialysis with nephrologist • Renal transplantation : to discuss after 2 years of dialysis (possible late recovery) By Dr.Pauline Martins @PaulineM8140 via Dr. Benjamin Terrier @TerrierBen #Scleroderma #RenalCrisis #Diagnosis #management #nephrology
