Syphilis - Diagnosis and Management - Primary vs Secondary vs Tertiary
Primary Syphilis
• Localized lymphadenopathy
• Chancres
Secondary Syphilis
• Headaches
• Uveitis, retinitis, optic neuritis, cranial nerve palsies
• Hepatitis
• Lymphadenopathy
• Glomerulonephritis
• Periostitis
Tertiary Syphilis
• Neurosyphilis (NS) if CSF shows:
- Pleiocytosis > 20 cells/mm3
- Hyperproteinorachia
- Positive VDRL (Se 30-40%)
- Negative treponemal tests rule out NS
• General paresis :
- Cognitive impairment
- Psychiatric manifestations
- Focal deficits
• Tabes dorsalis
• Aortic aneurysms ± valvular insufficiency
• Coronary ostium stenosis
by Dr. Maxime Beydon via via Dr. Benjamin Terrier @TerrierBen
#Syphilis #Primary #Secondary #Tertiary #Comparison #Diagnosis #Management #stages #staging
