Loiasis - Loa loa Life Cycle 1) Fly (genus Chrysops) takes a meal (L3 larvae enter bite wound) Human Stages: 2) Adults in subcutaneous tissue 3) Adults produce sheathed microfilariae that are found in spinal fluid, urine, sputum, peripheral blood and in the lungs 4) Fly takes a blood meal (ingests microfilariae) Fly Stages: 5) Microfilariae shed sheaths, penetrate fly's midgut, and migrate to thoracic muscles 6) L1 larvae 7) L3 larvae 8) Migrate to head and fly's proboscis #Loiasis #Loaloa #LifeCycle #diagnosis #pathophysiology #infectiousdiseases #cdc #parasite