APRV - Overview Airway pressure release ventilation (APRV) uses prolonged periods of high continuous positive airway pressures interrupted by brief episodes of pressure release to a lower pressure β’ Intended as a rescue therapy for severe ARDS (low lung compliance with high oxygenation requirements) Advantages: Alveolar recruitment and improved oxygenation, preservation of spontaneous breathing, lower sedation requirements Disadvantages: Risk of volutrauma, increased work of breathing and energy expenditure, consistently increased intrathoracic pressures may adversely affect hemodynamics M. Daniyal Hashmi, MD @MDaniyalHashmi1 #APRV #CriticalCare #Ventilation #Management #AirwayPressureRelease #Overview