Pathological Optic Disc Cupping Note cup-to-disc ratio at least 0.8 (physiologic limit of 0.5). Thinning of optic disc neuroretinal rim so that optic disc appears pathologically cupped (excavated). Usual cause is glaucoma. Glaucoma causes slow death of optic nerve axons and their supporting glia partly because of chronically high intraocular pressure. #OpticDisc #Cupping #fundoscopy #ophthalmology #Clinical
