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Acral Lentiginous Melanoma (involving nail) While acral lentinginous melenoma is often seen anywhere on the palms, soles, and even in the mouth, when it occurs within the nail, a clue that this is melanoma is involvement of the periungal regions as seen in this picture. #Acral #Lentiginous #Melanoma #Fingernails #PhysicalExam #Clinical #Photo #Sign