Recommended Follow-up of Treated Syphilis Cases EVIDENCE OF TREATMENT FAILURE OR POSSIBLE REINFECTION • Persistence or recurrence of signs and symptoms • A sustained (more than 2 weeks) 2-dilution (E, 4-fold) or more rise in nontreponemal titer following iritiation of treatment (as compared with initial baseline or subsequent results) POSSIBLY: Failure of nontreponemal titer to decrease 2 dilutions 4-fold) by 6-12 months post-treatment • The development of signs and symptoms • A sustained (more than 2 weeks) 2-ciilution (E, 4-fold) or greater rise in nontreponemal titer following initiation of treatment (as compared with initial baseline or subsequent results) • In patients with an initial titer 1:32, failure of the nontreponemal titer to decrease at least 2 dilutions (4-fold) by 12—24 months #Followup #Syphilis #Failure #Treatment #Management #Guidelines #CDC
