Primary Syphilis
Usually, a single ulcer (chancre) appears at the site where the bacteria entered the body. The
genitals are the most common location for chancres to develop, but these ulcers also can form
around the mouth or anus. The chancre is firm and painless, and it oozes fluid that contains
syphilis bacteria. Sometimes, lymph nodes near the ulcer become enlarged, but remain painless.
The chancre of primary syphilis usually heals after one to five weeks, although the person remains
infected.
▪ Painless lesion appears 10-90 days at site of exposure, persists for 1-5 weeks
▪ Multiple lesions (25% of patients)
▪ Often goes unnoticed if it’s not someplace obvious, i.e. inter-vaginally, rectally, orally
Primary syphilitic chancres are usually firm, round, small, and painless, and develop at the spot where the T. pallidum bacteria enter the body. The chancre lasts 1 to 5 weeks, and it heals without treatment. However, if adequate treatment is not administered, the infection progresses to the secondary stage.

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Dr. Gerald Diaz @GeraldMD · 4 years ago
Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief 🇵🇭 🇺🇸 - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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