Isocoria - Pupillary Defects - Differential Diagnosis Algorithm Relative Afferent Pupil Defect • Optic Neuritis • Ischemic Optic Neuropathies • Optic Nerve Tumor • Retinal detachment • Traumatic/Compressive Optic Neuropathy Constricted Pupils (Miotic) • Syphilis (light-near dissociation) • Pharmacologic (e.g Opioids, Alcohol) Dorsal Midbrain (Parinaud's Syndrome): • Tumor • Hemorrhage • Hydrocephalus Neuromuscular Junction Dysfunction: • Botulism Pharmacologic: • Atropine • LSD • Cocaine • Amphetamines #Isocoria #Pupillary #Pupils #Defects #Differential #Diagnosis #Algorithm #Causes #Ophthalmology
