Inflammatory Joint Pain - Differential Diagnosis Algorithm Monoarticular • Gout (Podagra, Tophi) • Pseudogout • Early Rheumatic Disease • Reactive (e.g. Genitourinary Infection) Oligoarticular (1-4 joints) • Gout • Psoriatic (Nail Changes, Plaques) • Enteropathic (e.g. Inflammatory Bowel Disease) • Reactive • Rheumatic Fever (recent Pharyngitis, Carditis) • Lyme Disease (Tick bite, Migratory red Macules) POLYARTICULAR (>4 joints) Subacute & Symmetrical • Rheumatoid Arthritis • Systemic Lupus Erythematosus • Sjögren's (a.k.a. Sicca) Syndrome • Scleroderma • Henoch-Schonlein Purpura • Polymyalgia Rheumatica • Granulomatosis with polyangiitis (GPA)/microscopic polyangiitis (MPA) Insidious Monoarticular • Symmetric (Polymyositis/Dermatomyositis) • Asymmetric (Psoriatic Arthritis) Migratory • Rheumatic Fever Acute Onset • Reactive Insidious Onset • Ankylosing Spondylitis • Enteropathic (e.g. Inflammatory Bowel Disease) • Psoriatic Arthritis #Inflammatory #JointPain #MSK #Differential #Diagnosis #Algorithm #Orthopedics #Causes
