On the left a typical case of panlobular emphysema. There is uniform destruction of the underlying architecture of the secondary pulmonary lobules, leading to widespread areas of abnormally low attenuation. Pulmonary vessels in the affected lung appear fewer and smaller than normal. Panlobular emphysema is diffuse and is most severe in the lower lobes. In severe panlobular emphysema, the characteristic appearance of extensive lung destruction and the associated paucity of vascular markings are easily distinguishable from normal lung parenchyma. On the other hand, mild and even moderately severe panlobular emphysema can be very subtle and difficult to detect on HRCT(1). #Clinical #Radiology #CTChest #Panlobular #Emphysema #PanlobularEmphysema #RadiologyAssistant