Diffuse Systemic Sclerosis (Scleroderma) - Pulmonary Fibrosis -> Crackles, Abnormal CXR - Pulmonary Hypertension, Right Heart Failure - Arrhythmias; Left Heart Failure - Esophageal Dysmotility -> esophageal dilation, reflux - Gastric Ectasia (Watermelon Stomach) - Lower GI Tract dysmotility -> bacterial overgrowth -> diarrhea - Malignant HTN -> Renal Failure - Mask Facies (i.e. a "purse-string mouth" with decr openinq) - Calcinosis cutis (irregular, hard nodules under skin) - Sclerodactyly (swollen fingers) - Finger/hand/elbow contractures - Tendon friction rub - Red fingers/toes - Raynaud's Phenomenon - Decr blood flow into extremities -> White fingers/toes - O2 extracted from blood already there -> Blue fingers/toes - Peri-ungal capillary loops become dilated, prominent, and bushy - Finger pulp atrophy - Telangiectasia - Digital Ulcerations #Diffuse #SystemicSclerosis #Scleroderma #pathophysiology #signs #symptoms #diagnosis
