Psoriatic Arthritis: Pathogenesis and Clinical findings

In tendons and connective tissues:
 • Enthesitis  - Pain/tenderness over ligament insertion into bone
 • Dactylitis - Inflammation of entire digit- soft tissue and joints are inflamed
In skin:
 • Psoriatic plaques on skin, pitting, ridging, oil spots, onycholysis, discoloration and hyperkeratosis
In Joints:
    1. Asymmetric oligoarthritis
    2. Arthritis of DIP joints
    3. Symmetric polyarthritis (like RA)
    4. Axial involvement (unknown reason, probably due to "biomechanical", "innervation" & "vascularity")
    5. Arthritis mutilans (aggressive & destructive)
 • X-ray: Periostitis; syndesmophytes, erosions, pencil in cup deformities due to osteolysis (IP joints), ankylosois of IP joints

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The Calgary Guide to Understanding Disease @TheCalgaryGuide · 4 years ago
Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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