Pathogenesis of Anxiety Disorders
Anxiety Disorders: A maladaptive emotional state causing fear,
worry, and excessive stress, characterized by:
- Physiological arousal
- Unpleasant tension
- Sense of foreboding or apprehension
• Female gender (may be related to hormonal factors, less internal locus of control, greater reporting rates)
• Genetics (Positive family history)
• Other biological theories (under investigation)
• Predisposition to anxiety: Imbalance and/or abnormal functioning of norepinephrine, serotonin, dopamine, and gamma-aminobutyric acid (GABA)
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