Acquired Disorders of Reduced Bone Strength: Pathogenesis
• Hyperparathyroidism
• Vitamin D deficiency
• Malabsorption syndromes
• Chronic metabolic acidosis
• Physical activity
• Smoking
• Diabetes
• Other causes of bone mineralization defect
• Protein-calorie malnutrition
• Thyrotoxicosis
• Menopause
• Decreased Testosterone in men
• Aromatase inhibitors
• Malignancies (e.g., multiple myeloma lymphoma, leukemia)
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