Scoliosis: Pathogenesis and clinical findings (Cobb Angle > 10 Degrees) • Incr Axial rotation of thoracic vertebrae is transferred through the costovertebral joints to the ribs -> The rib cage is rotated and displaced in the transverse plane -> Rib Hump (unilateral prominence of the rib cage) • Incr lateral curvature of the spine is transferred through the sacroiliac joints to the pelvis -> The pelvis is tilted and displaced in the transverse plane -> Asymmetrical Iliac Crests, Shoulders. Scapula and/or Breasts, Apparent Leg and/or Arm Length Discrepancy • Incr Lateral curvature of the spine narrows the intervertebral canal -> Spinal nerve impingement -> Neuropathy, pack pain • Incr lateral curvature and/or axial rotation of the thoracic vertebra (Cobb Angle > 40 degrees) -> Thoracic cage deformity in the coronal and/or transverse plane -> Decr thoracic volume -> Decr lung expansion -> Decr lung compliance -> Shortness of Breath On Exertion, Restrictive Pulmonary Disease, Right Sided Heart Failure #Scoliosis #pathophysiology #msk #diagnosis #signs #symptoms