Septic Arthritis: Pathogenesis and clinical findings Notes: - Septic Arthritis is typically monoarticular & the knee is involved in >50% of cases - decr blood flow, impaired local immunity, potential for biofilm formation - Typical S.A joint aspirate: opaque clarity, >50000 WBC/mm3 with >50% neutrophils, low viscosity & often a +ve culture Microbiology: - Bacterial infection is most common, but S.A. can also be caused by, fungi, viruses, and mycobacterium - S. aureus = most common non-gonnococcal pathogen across all age groups - Always consider N. gonorrhoeae in young adults #SepticArthritis #pathophysiology #diagnosis
