Breast Discharge - Differential Diagnosis Algorithm High Prolactin + Normal TSH • Microprolactinoma • Steroid Hormone Intake • Chronic Renal Failure • Stress (e.g. Pregnancy, Breast Stimulation, Trauma/Surgery) High Prolactin + Normal/ Low TSH • Pituitary Macroadenoma • Dopamine Inhibition • Pituitary Stalk Compression/Lesion Autonomous Production • Renal Cancer or Failure • Lactotroph Adenoma • Bronchogenic Tumor • Contraceptive Pill/Patch/Ring High Prolactin + High TSH • Primary Hypothyroidism #Breast #Discharge #Differential #Diagnosis #Algorithm #Endocrinology #Causes
