Aqueous Humor Production and Drainage • Provides nutrition, removes wastes, and transports neurotransmitters to the avascular lens and cornea. • Circulates inflammatory cells to avascular structures • Maintains structural integrity of ocular structures via intraocular pressure (10-21 mmHg) AH leaves the anterior chamber via two pathways located near the limbus: • Trabecular Meshwork Pathway (~60-80 % of flow) -> AH passes through the TM layers: Uveal, corneoscleral, and juxtacanalicular -> Flows into Schlemm's Canal -> Flows through internal outflow channels into the external outflow channels, aqueous veins, intrascleral venous plexus, and the deep scleral venous plexus -> Drains into the episcleral and conjunctival veins -> Drains back into systemic venous circulation • Uveoscleral Pathway (~20-40 % of flow) -> AH enters uveal meshwork and anterior ciliary body -> Flows in suprachoroidal space -> Passes outward through the sclera -> Enters the scleral, and conjunctival veins -> Drains back into systemic venous circulation #AqueousHumor #Production #Drainage #flow #Pathophysiology #ophthalmology
