Retinitis Pigmentosa: Pathogenesis and Ocular Manifestations • Inherited mutation of rhodopsin gene -> Mode of inheritance may be autosomal dominant, autosomal recessive, or X-Iinked • Sporadic mutation of rhodopsin gene -> Abnormal photoreceptor protein production => Retinitis Pigmentosa • Mild arteriolar narrowing • Severe arteriolar narrowing • Epiretinal membrane formation • Macular atrophy • Cystoid macular edema => Blindness #RetinitisPigmentosa #pathophysiology #ophthalmology
