Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal involvement with 2 1 of'
• respiratory compromise
• hypotension
2. Rapid onset of symptoms after exposure to a likely allergen with >2 of:
• skin/mucosal symptoms
• respiratory symptoms
• hypotension
• persistent GI symptoms
3. Hypotension after exposure to known allergen
Note: Severity of symptoms in the acute phase does not necessarily predict occurrence of late phase symptoms
Signs / Symptoms / Complications:
• Abdominal cramping, vomiting, diarrhea
• Wheezing, dyspnea, hypoxia
• Angioedema
• Flushing
• Hypotension -> Circulatory collapse ->
- Neurological Compromise (e.g. syncope, seizures)
- Cardiac Compromise (e.g. arrythmias, ischemia)
• Urticaria
• Angioedema
#Anaphylaxis #pathophysiology #immunology #diagnosis #signs #symptoms