Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging of head/spine • Returning traveler? Refer to your ‘Fever in a Returning Traveler’ algorithm • Travel to Midwest or Southeast? Test for the respective fungal pathogens based on geography • Travel to malaria–endemic regions? Thick and thin smear • Signs of VTE? Venous duplex or CTA • Liver lesions? Liver biopsy • Lymphadenopathy? Lymph node biopsy • Clinical findings of PAN? Temporal artery biopsy • Lab values supporting hematologic malignancies? Bone marrow biopsy Dr. Uday Gulati @udaygulati #FUO #Fever #UnknownOrigin #workup #diagnosis
