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Hyperphosphatemia - Differential Diagnosis Algorithm Transcellular Shift: • Rhabdomyolysis • Tumor Lysis • Metabolic or Respiratory Acidosis • Insulin Deficiency Decreased Excretion FE PO4 < 20%: • Renal Disease • Hypoparathyroidism • Pseudo-hypoparathyroidism • Acromegaly • Bisphosphonate Therapy Increased Intake / Absorption - Normally in Context of Impaired Renal Function: • Hypervitaminosis D • Phosphate Supplementation • Phosphate Containing Enemas/Laxatives Pseudo-hyperphosphatemia: • Multiple Myeloma Hyperbilirubinemia • Hemolysis • Hyperlipidemia • Tumor Lysis #Hyperphosphatemia #HighPhosphate #Differential #Diagnosis #Algorithm #endocrinology #causes