Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short Stature Normal Variant, Delayed Puberty Onset (BA < CA) • Constitutional Short Stature (Late Bloomer) Disproportionate • Skeletal Dysplasias • (e.g. Achondroplasia) • Rickets Dysmorphic Features • Trisomy 21 • Noonan Syndrome • Prader-Willi Syndrome • Russell-Silver Syndrome • Turner Syndrome Deprivation • Primary Malnutrition • Psychosocial • Deprivation Endrocrine • Cushing's Disease • GH Deficiency • IGF-I Deficiency (e.g. Laron Dwarfism) • Hypothyroidism • Congenital Adrenal Hyperplasia • Panhypopituitarism Treatment • Glucocorticoids • Radiation • Chemotherapy • Bone Marrow Transplant Chronic Disease • GI (e.g. Celiac, IBD) • Renal (e.g. CRF) • Infection (e.g. Chronic UTI) • Cardiopulmonary (e.g. Cystic Fibrosis, CHF) • Inborn Metabolism Error • Immunologic Other • Intrauterine Growth Retardation • Bulimia Nervosa • Anorexia Nervosa • CNS Tumors (e.g. Craniopharyngioma) #ShortStature #Differential #Diagnosis #Algorithm #endocrinology #causes #pediatrics
