Mucous Membrane Disorder - Differential Diagnosis Algorithm
Erosions/Ulcers/Blisters
- Primary Dermatologic Diseases
• Aphthous Stomatitis (recurrent, punched out ulcers, often preceded by trauma/emotional stress)
• Herpetic gingivostomatitis
• Pemphigus vulgaris
• Bullous pemphigoid
• Erythema multiforme
• Stevens-Johnson Syndrome
• Toxic epidermal necrolysis
- Systemic Disease
• Systemic lupus erythematosus
• Inflammatory bowel disease (ulcerative colitis more than Crohn's disease)
• Behcet's syndrome
White Lesions
- Neoplastic
• Leukoplakia
• Squamous cell carcinoma
- Candidiasis - White/cottage cheese like plaques/scrape off easily
- Lichen Planus - Reticular (lace-like) white lines & papules
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