Effects of a Low-Protein, Low-Salt Diet on the Afferent Arteriole. A lower intake of dietary protein leads to greater constriction of the afferent arteriole. Thus, a low-protein diet results in incremental reductions in the glomerular filtration rate, but over time, a sustained low-protein diet has been observed to diminish glomerular damage and stabilize or improve function. #Pathophys #Nephro #CKD #LowProteinDiet #GFR #NEJM