Skin Ulcers by Etiology - Differential Diagnosis Algorithm
Physical:
• Trauma
• Pressure
• Radiation
Vascular:
• Arterial Insufficiency
• Venous insufficiency
• Vasculitis
Neoplastic:
• Squamous cell carcinoma
• Basal cell carcinoma
• Melanoma
• Mycosis fungoides (cutaneous T-cell lymphoma)
Neurological:
• Diabetic neuropathy
• Tabes dorsalis (syphilis)
• Factitious disorder
• Delusions of parasitosis
Metabolic:
• Pyoderma gangrenosum
• Diabetic dermopathy
• Necrobiosis lipoidica
Drugs:
• Coumadin
• Heparin
• Bleomycin
Hematologic:
• Sickle Cell Anemia
• Thalessemia
• Cryoglobulinemia
Infectious:
- Protozoan - Leishmaniasis
- Viral - Herpes simplex
- Bacterial
• Tuberculosis
• Syphilis
• Chlamydia trachomatis
• Klebsiella granulomatis
- Fungal
• Histoplasmosis
• Coccidioidomycosis
• Cryptococcosis
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