Chest Pain - Differential Diagnosis Algorithm
Cardiovascular Causes:
- Outflow Obstruction
• Aortic Stenosis
- Ischemic
• Myocardial Infarction
• Stable/Unstable Angina
- Non-lschemic
• Aortic Dissection
• Dilating Aneurysm
• Pericarditis
• Myocarditis
Pulmonary / Mediastinal Causes:
- Vascular
• Pulmonary Embolism (chest pain often not present)
• Pulmonary Hypertension
- Chest Wall/Pleura
• Pneumothorax
• Pleural Effusion
• Pleuritis/Serositis
- Parenchymal
• Pneumonia with pleurisy
• Tuberculosis
• Neoplasm
• Sarcoidosis
Other Causes:
- Gastrointestinal
• Gastro-Esophageal Reflux Disease
• Biliary Disease
• Peptic Ulcer Disease
• Pancreatitis
• Esophageal Spasm
• Esophageal Perforation
- Musculoskeletal
• Costochondritis
• Muscular Injury
• Trauma
- Neurologic/Psychiatric
• Anxiety/Panic
• Herpes Simplex Virus/Post-Herpetic Neuralgia
• Somatoform Disorder
• Spinal Radiculopathy
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