Causes of Hyperkalemia - Reduced Excretion - Differential Diagnosis Algorithm Reduced flow through distal nephron - TTKG > 7, Urine Na < 20 meq/L • Low EABV (e.g., CHF, cirrhosis, hypotension) Decreased Glomerular Filtration Rate - Increased Creatinine • Chronic renal failure • AKI High Renin, High Aldosterone • ENaC blockers • AIN/CIN • Obstruction High Renin, Low Aldosterone • ACEi/ARB • Adrenal insufficiency • Heparin Low Renin, Low Aldosterone • Diabetic nephropathy • Beta-2 antagonism • NSAlDs #Hyperkalemia #IntercellularShift #Nephrology #Differential #Diagnosis #Algorithm #Causes
