Causes of Nephrolithiasis - Differential Diagnosis Algorithm
Radio-opaque - Calcium-containing - 90% of stones
Radiolucent - Non-calcium 10% of stones
Uric Acid Stones:
• Hyperuricosuria
• High protein intake
Soft Stones - Struvite Stones - 10% of stones:
 • Urinary tract infection
Cysteine Stones - Non Calcium containing, but opaque:
 • Cystinuria
Hypercalciuria:
 • Increased PTH
 • High salt intake
 • High protein intake
Hyperoxaluria:
 • Enteric overproduction
 • Low calcium intake
 • Dietary
 • Ethylene glycol ingestion
Stones with decreased solubility:
 • Low urine volume
 • Hypocitraturia
 • RTA Type I
 • High protein intake
Anatomical problem:
 • Medullary sponge kidney

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Calgary Blackbook @CalgaryBlackBook · 4 years ago
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