Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
• Decreased Production
• Increased Destruction
• Abnormal Sequestration
Disordered Platelet Function - Qualitative Defect
• Congenital - Rare
• Drugs (e.g. ASA)
• Renal Disease
Vascular System - Congenital
• Connective Tissue Disorders
• Hereditary TeIangiectasia
Vascular System - Acquired
• Steroids
• Vasculitis
Coagulation Proteins - Congenital
• Factor VIII Deficiency
• Factor IX Deficiency
• Von Willebrand's Disease
• Other deficiencies
Coagulation Proteins - Acquired
• Anticoagulation (Iatrogenic)
• Liver Disease
• Vitamin K Deficiency
• Disseminated Intravascular Coagulation
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