Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive • Cirrhosis • Thrombus (e.g. Hepatic, Portal, Splenic) Infiltrative - Non-Malignant • Amyloidosis • Gaucher's Disease • Glycogen Storage Disease Infiltrative - Malignant • Lymphoma • Leukemia • Myeloproliferative disorders (eg. polycythemia vera, essential thrombocytosis, myelofibrosis) Inflammatory • Systemic Lupus Erythematosus • Sarcoidosis • Felty's Disease • Serum Sickness Hemolytic Disease • Sickle Cell Disease (children) • Thalassemia • Congenital Spherocytosis • Acquired causes #Splenomegaly #Spleen #Enlarged #Differential #Diagnosis #Algorithm #Causes #Hematology
