Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm
Cervical:
- Anterior
• Infection (e.g. Mononucleosis, Toxoplasmosis)
- Posterior
•TB
• Lymphoma
• Kikuchi Disease
• Head/Neck Malignancy
Supraclavicular:
• Thoracic Malignancy (Breast, Mediastinum, Lungs, Esophagus)
• Abdominal Malignancy (Virchow's Node)
Axillary:
• Infection (Arm, Thoracic Wall, Breast)
• Cancer (In absence of infection in upper extremity)
Epitrochlear (Always pathologic):
• Infection (Forearm/Hand)
• Lymphoma
• Sarcoidosis
• Tularemia
• Secondary Syphilis
Inguinal:
• Leg Infection
• Sexually Transmitted Infection
• Cancer
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