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Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia Vera • Chronic Myelogenous Leukemia • Primary Myelofibrosis Infectious: • Acute or Chronic Inflammatory: • IBD • Rheumatic disorders • Celiac disease Tissue Damage: • Post-op surgery • Trauma • Burns Non malignant hematologic conditions: • Rebound effect following treatment of ITP • Rebound effect following EtOH induced thrombocytopenia Other: • Post-splenectomy or hyposplenic states • Non-hematologic malignancy • Iron deficiency anemia #Thrombocytosis #Differential #Diagnosis #Algorithm #Causes #Hematology