Causes of Growth Discrepancy: Large for Gestational Age - Differential Diagnosis Algorithm Maternal Factors: • Multiparity • Previous history of large for gestational age fetus • Aboriginal, Hispanic, and Caucasian races • Maternal co-morbidities (e.g. diabetes, obesity) • Excessive weight gain over course of pregnancy (>40 lbs) Maternal Complications: • Prolonged labour • Operative vaginal delivery • Caesarean section • Genital tract lacerations • Post-partum hemorrhage • Uterine rupture Fetal Factors: • Male infant • Prolonged gestation (>41 weeks) • Genetic disorder (e.g. Sotos syndrome, Beckwith-Wiedemann syndrome, Weaver's syndrome) Fetal Complications: • Shoulder dystocia • Birth injury (brachial plexus injury, clavicular fracture) • Cerebral palsy secondary to hypoxia • Hypoglycemia • Polycythemia • Perinatal asphyxia • Hyperbilirubinemia #Large #GestationalAge #LGA #Complications #Pregnancy #Differential #Diagnosis #Algorithm #Causes #Obstetrics #OBGyn
