Causes of Male Infertility - Differential Diagnosis Algorithm Sperm Transport: • Vasectomy • Cystic fibrosis gene mutation • Post-infectious obstruction • Ejaculatory duct cysts (e.g. prostate) • Kartagener syndrome Sexual Dysfunction Sperm Motility - Abnormal semen analysis: • Antibodies from infection Pre-Testicular (Hypogonadotrophic hypogonadism) Low FSH/LH: • Kallmann syndrome • Suppression of gonadotropins (e.g. hyperprolactinemia, hypothyroidism, drugs, tumor, infection, trauma) • Anabolic steroids Testicular - (Sperm production problem) High FSH/LH: • Genetic abnormality (e.g. Klinefelter's) • Cryptorchidism • Varicocele • Mumps orchitis • Radiation, Infection, drugs, trauma, torsion #Male #Infertility #Differential #Diagnosis #Algorithm #Causes #PrimaryCare
