Causes of Recurrent Pregnancy Loss - Differential Diagnosis Algorithm Environmental: • Toxin (organic solvents, mercury, lead) • Smoking • Alcohol • Drugs • Ionizing radiation Other: • Maternal infection • Thrombophilia Autoimmune: • Antiphospholipid syndrome • Lupus anticoagulant Endocrine: • Diabetes mellitus • Hypo/hyperthyroidism • PCOS • Luteal phase deficiency Genetic: • Maternal age • Maternal / paternal chromosomal abnormality Cervix: • Cervical insufficiency Uterus: • Fibroids • Congenital anomaly • Polyps • Asherman's Syndrome #Recurrent #Pregnancy #Loss #Spontaneous #Abortion #Differential #Diagnosis #Algorithm #Causes #Obstetrics #OBGyn
