Causes of Congenital Anomalies - Differential Diagnosis Algorithm Malformation • Embryonic development failure or inadequacy (often multifactorial) Deformation • Abnormal mechanical forces distorting otherwise normal structures (e.g.exoligohydramnios) Disruption • Destruction/ Breakdown of previously normal tissue (e.g. ischemia) Association of Anomalies (Syndromic) • Chromosomal • Single Gene • Teratogenic • Association (e.g. VACTERL) #Congenital #Anomalies #Anomaly #Differential #Diagnosis #Algorithm #Causes #Peds #Pediatrics
