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Causes of Apparent Life Threatening Event (ALTE) - Differential Diagnosis Algorithm Cardiac: • Congenital Heart Disease • Arrhythmia • Cardiomyopathy • Myocarditis Metabolic: • Inborn Errors of Metabolism • Reye's Syndrome • Electrolyte Disturbances Neurologic: • Seizure • Malignancy • Neuromuscular • Disorders • Central Apnea Respiratory: • Anatomical Foreign Body Aspiration • Breath-holding spell (age-dependent) Infectious: • Pneumonia • Sepsis • Upper Respiratory Tract Infection • Empyema • Urinary Tract Infection Gastrointestinal: • Gastroesophageal Reflux • Volvulus • Gastroenteritis • Incarcerated Hernia Witnessed Choking Spell Injury: • Non-Accidental • Unnoticed • Factitious by Proxy Apnea: • Periodic Breathing • Apnea of Infancy #LifeThreatening #Event #ALTE #BRUE #Differential #Diagnosis #Algorithm #Causes #Peds #Pediatrics