Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic symptoms, and less response to therapy. Dermatomyositis can present with rash including heliotrope rash, Shaw sign, holster sign, and Gottron's papules 30% w/ anti-synthetase syndrome- Classic triad of ILD, myositis, and arthritis (19% w/full triad at diagnosis). Can also see mechanics hands. Around half of anti-SRP and anti-HMGCR myopathy patients continue to have significant weakness after 2 years of treatment. by Dr. Ann Marie Kumfer @AnnKumfer #Autoimmune #Myositis #diagnosis #rheumatology
