PDE5 inhibitors are usually the drugs of first choice for erectile dysfunction. PDE5 inhibitors enhance an erection that is partially developing as a result of effective sexual stimulation and mental sexual arousal. Drug interactions with PDE5 inhibitors include alpha blockers and CYP3A4 inhibitors - which can be used concomitantly with caution - e.g. at lower doses. PDE5 inhibitors should not be used with nitrates due to serious and potentially fatal hypotension - and should be separated by 12 - 48 hours (depending on the drug). #pharmacology #comparison #treatment #medications #dosing #drugs #table #pharmacotherapy
