Clinical Characteristics of Simple vs Complex Cutaneous Leishmaniasis Simple CL - Caused by a Leishmania species unlikely to be associated with mucosal leishmaniasis - No mucosal involvement noted - Only a single or a few skin lesions - Small lesion size (diameter <1 cm) Complex CL: Caused by a Leishmania species that can be associated with increased risk for ML, particularly Viannia spp in the “mucosal belt” of Bolivia, Peru, and Brazil - Local subcutaneous nodules, Large regional adenopathy - >4 skin lesions of substantial size (eg, >1 cm), Large individual skin lesion (diameter ≥5 cm) #Simple #Complex #Cutaneous #Leishmaniasis #diagnosis #comparison #table