Tuberculosis Dosing Recommendations for Adult Patients With Reduced Renal Function (CKD) Isoniazid 300 mg once daily, or 900 mg 3 times/wk Rifampin 600 mg once daily, or 600 mg 3 times/wk Pyrazinamide 25–35 mg/kg/dose 3 times/wk (not daily) Ethambutol 20–25 mg/kg/dose 3 times/wk (not daily) Levofloxacin 750–1000 mg/dose 3 times/wk (not daily) Moxifloxacin 400 mg once daily Cycloserine 250 mg once daily, or 500 mg/dose 3 times/wkb Ethionamide 250–500 mg/dose daily Para-amino salicylic acid 4 g/dose twice daily Streptomycin 15 mg/kg/dose 2-3 times/wk (not daily) Capreomycin 15 mg/kg/dose 2-3 times/wk (not daily) Kanamycin 15 mg/kg/dose 2-3 times/wk (not daily) Amikacin 15 mg/kg/dose 2-3 times/wk (not daily) #Tuberculosis #Dosing #CKD #pharmacology #medications #management #Drugs