IDSA Diabetic Foot infection - In Which Situations Is Diagnostic Bone Biopsy Most Recommended? • Patient or provider prefers definitive diagnosis to justify choice of early surgery in favor of prolonged treatment • Cultures of soft tissue or blood suggest high risk of osteomyelitis with antibiotic-resistant organism(s) • There is progressive bony deterioration or persistently elevated inflammatory markers during empiric or culture directed therapy (should consider surgical resection) • Suspect bone is a planned target for insertion of orthopaedic metalware #IDSA #Diabetic #Foot #infection #Bone #Biopsy #Indications
