IDSA Recommendations for Treating Mucosal Candidiasis in HIV-AIDS Oropharyngeal Candidiasis: Initial Episodes (Duration of Therapy: 7–14 days) Preferred Therapy: • Fluconazole 100 mg PO once daily (AI), or Alternative Therapy: • Clotrimazole troches 10 mg PO 5 times daily (BI), or • Miconazole mucoadhesive buccal tablet 50 mg: Apply to mucosal surface over the canine fossa once daily (do not swallow, chew, or crush tablet). Refer to product label for more detailed application instructions, (BI) or • Itraconazole oral solution 200 mg PO daily (BI), or • Posaconazole oral suspension 400 mg PO BID for one day, then 400 mg daily (BI), or • Nystatin suspension 4–6 mL QID or 1–2 flavored pastilles 4–5 times daily (BII) Esophageal candidiasis (Duration of Therapy: 14–21 days) Note: Systemic antifungals are required for effective treatment of esophageal candidiasis (AI) Preferred Therapy: • Fluconazole 100 mg (up to 400 mg) PO or IV daily (AI), or • Itraconazole oral solution 200 mg PO daily (AI) #esophageal #Candidiasis #candida #mucosal #IDSA #Prevention #Treatment #management #opportunistic #infections #HIVAIDS #pharmacology
