Intern Pocket Cards - Inpatient Anti-Emetics Guide
Serotonin antagonists:
• Ondansetron (Zofran), Granisetron (Kytril, Sancuso) - Headache, constipation, drowsiness, diarrhea
Dopamine antagonists (DA):
• Metoclopramide (Reglan) -Drowsiness, EPS, do not use if increased GI motility
• Olanzapine (Zyprexa) - EPS, hyperglycemia
• Prochlorperazine (Compazine) - EPS, NMS
• Haloperidol (Haldol) - EPS, constipation, dry mouth, blurred vision, somnolence
• Chlorpromazine (Thorazine) - EPS, dry mouth
Histamine antagonists:
• Diphenhydramine (Benadryl) - Dizziness, drowsiness, paradoxical excitation
ACh antagonists
• Scopolamine - Bradycardia, flushing, thirst, xerostomia, urinary retention
DA/Histamine/ACh antagonist:
• Promethazine (Phenergan) - EPS, NMS, drowsiness, sedation, leukopenia, thrombocytopenia
Neurokinin-1 receptor antagonists
• Aprepitant (Emend) - Hiccups, bradycardia, neutropenia
• Fosaprepitant (Ivemend) - Angioedema, bradycardia, neutropenia
Centrally acting:
• Dexamethasone - Leukocytosis, mood changes, adrenal suppression, hyperglycemia
• Trimethobenzamide (Tigan) - EPS, disorientation, seizure
• THC, dronabinol - Hyperemesis, tachycardia, nystagmus, ataxia
• Lorazepam (Ativan) - Respiratory depression
Dr. Satya Patel @SatyaPatelMD
Full Inpatient Pocket Cards Collection: https://bit.ly/pocketcardset
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