Noninvasive Positive Pressure Ventilation (NIPPV)

Expiratory & Inspiratory Positive Airway Pressure
Both increase intrathoracic pressure, which can decrease venous return.
Both can decrease LV afterload by reducing LV transmural pressure, potentially improving SV.
EPAP prevents upper & lower airway collapse and can "recruit" alveoli'.
IPAP can help generate larger VT and decreases respiratory fatigue, especially in obstructive lung and neuromuscular disease.
CPAP - Continuous Positive Airway Pressure - Provides EPAP. In CHF, decreases intubation and mortality
BPAP - Bi-Level Positive Airway Pressure - Provides both EPAP and IPAP. In COPD, decreases intubation, mortality, LOS
NIPPV Indications:
 • CHF exacerbation (cardiogenic pulmonary edema)
 • COPD exacerbation (often w/ acute on chronic resp acidosis)
 • Post-extubation in high risk patients (ie., CHF or COPD)
 • Other acute respiratory failure (ie.. asthma exacerbation)
 • Chronic respiratory failure (ie OHS and neuromuscular dz)
 • Pt is DNI with indication for intubation
 • Palliation for increased WOB, dyspnea
NIPPV Contraindications:
 • Risk of Aspiration - unable to clear secretions, altered mental status
 • Won't Work - Cannot initiate breath, Anatomic deformity (facial trauma, surgery, excess facial hair)
 • Risk Of Clinical Worsening - Cannot tolerate decreased preload, Recent intrathoracic damage (pneumothorax. esophageal injury, intrathoracic procedure/surgery)

Dr. Meredith Greer @EmmGeezee

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Dr. Gerald Diaz @GeraldMD · 4 years ago
Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief 🇵🇭 🇺🇸 - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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