HSCT related renal disease - AKI and CKD
Acute Kidney Injury: Acute GvHD 2-4, Pre renal state, Antibiotics, Sepsis, Acyclovir, Amp B, ACE Inhibitor use, Contrast, Calcineurin Inhibitors, Veno occlusive disease(VOD)
Chronic Kidney Disease:
• Glomerular Diseases - Membranous Nephropathy (75%), Minimal Change Diseases, FSGS, Proliferative GN
• Viral: BK virus, CMV virus, Adenovirus, HHV6 and 8
• TMA: Calcineurin inhibitors, Viruses, GVHD, Conditioning regimen, Total body irradiation, Complement deficiencies
• Idiopathic: GVHD
Dr. Kenar Jhaveri @kdjhaveri
#stemcell #transplant #HSCT #renal #disease #AKI #differential #diagnosis #algorithm