Causes of Hypomagnesemia - Differential Diagnosis Algorithm GI LOSS - FeMg < 2-2.5% or 24h Urine Mg < 10g • Diarrhea • PPI use • Malabsorption RENAL LOSS - FeMg > 2-2.5% or 24h Urine Mg > 10g • Loop Diuretics • Hypercalcemia-PTH effect • Cisplatin, Amp B, Pentamadine, CNIs • Familial hypomagnesemia with hypercalciuria and nephrocalcinosis (FHHNC) • Gitelman's syndrome • Thiazide Diuretics • Cetuximab and other EGFR ab • Genetics defects in Na-KATPase, EGFR,HNF-1beta, cyclin M2 - Dr. Kenar Jhaveri @kdjhaveri #Hypomagnesemia #Magnesium #Low #Causes #Differential #Diagnosis #Algorithm
