Relapsing Acute Severe Ulcerative Colitis - Management Algorithm
Loss of Response:
• (Re)consult Colorectal Surgery
• Assess Adherence
• Assess Disease Activity: Flex Sig, FCP, CRP
• Rule OutC. Diff. & CMV COVID)
• TDM: IFX/CNl/VDZ Trough
• If c/f Complication: Cross-Sectional Imaging
• Urgent surgery: Fulminant UC, Toxic Megacolon, Systemic Toxicity, Patient Preference
Key Points:
• Consult Colorectal Surgery ASAP with Regular Follow up
• Surgery ≠ Treatment Failure
• If Hesitant for Surgery → Multidisciplinary Meeting with Patient and Family
• RD Referral to Optimize Nutrition
• CNI + Steroid +IS → PJP Prophylaxis
Algorithm by Dr. Waseem Ahmed @Waseem_AhmedMD
#Relapsing #Ulcerative #Colitis #UC #Management #Algorithm #IBD #Treatment